Aquilion ONE

- Aquilion ONE™: Wolrd’s First Dynamic Volume CT System
  In 2007, the history of CT changed again with the introduction of 160mm wide Dynamic Volume CT. The Aquilion ONE revolutionized Computed Tomography as its unique features opened the way to diagnose a larger patient population and more diseases than ever before. Next to the standard anatomical imaging, you now have access to high resolution isotropic 160mm wide Dynamic Volume CT to diagnose morphology, joint movements or even patients with cardiac arrhythmia. This leap is only possible with Canon’s Aquilion ONE, the only scanner with 160mm coverage and a 320-row detector.
  ONE Rotation
  
  The wide 160mm wide coverage eliminates the need for helical scanning when scanning heart, brain or other organs. The short one rotation scan procedures not only reduces the risk for patient or cardiac movement, but also lowers the exposed dose and minimizes the amount of contrast media needed.
  
  ONE Phase
  
  The entire heart can be captured in one rotation and within one isotropic phase, the sophisticated software allows you to scan patients with arrhythmia while maintaining an extremely high success rate. Each scan provides incredible motion-free images of the coronary arteries with homogenous contrast enhancement.
  
  ONE Volume
  
  The ability to acquire complete organs without helical movement opens the door to new diagnostic possibilities. The Neuro ONE volume protocol for example allows you to acquire a complete native brain together with multiple contrast enhanced low-dose volume scans resulting in a complete acute stroke workup within 5min. Dynamic volumetric acquisition protocols are also used to review moving joint structures in 3D, dynamic blood or air flow and provide you with new clinical applications and extending diagnosis.
- Specific Features
  Changing Clinical Pathways
  - Industry’s first Dynamic Volume CT scanner with the capability to acquire 16cm of anatomy in a single rotation.
  - Industry’s only whole-brain, 4D CT-DSA and perfusion in ONE exam
  - Industry’s fastest acute stroke work-up: 4.5min
  - The ability to acquire anatomical and functional data simultaneously to change and improve clinical pathways.
  Ultra Low Dose Examination
  
  Aquilion ONE incorporates Canon’s latest technologies to reduce exposure dose, while maintaining high image quality:
  - AIDR 3D (Adaptive Iterative Dose Reduction 3D)
  - Active collimator
  - ^SUREExposure™ 3D Adaptive (automatic exposure control)
  - ^SUREExposure Cardiac
  - Dose report
  Ultra Fast Workflow
  
  Aquilion ONE ensures a short time to diagnosis even for the most complex examinations providing the information needed to start the best treatment.
  - High-speed volume reconstruction system
  - 160-detector row helical
  - 78cm gantry aperture
  - Metal-free head rest
  - Metal-free arm up-holder
  - ^SUREXtension remote viewing station
  ONE Family Application
  
  A sophisticated suite of clinical applications, especially developed for Aquilion ONE™.
  - ^SURECardio
  - Myocardial Perfusion
  - ^SURESubtraction
  - ^SURESubtraction Lung
  - ^SURESubtraction Ortho
  - Dual Energy Analysis
  - SEMAR, Single Energy Metal Artefact Reduction
- Morphological Scanning
  A wide variety of scan methods can be selected according to the study objective and scan range.
  - Volume Scan
    Volume scan covers a range of up to 160mm so that organs as the brain and the heart can be scanned in a single axial scan. Since the overlap required in helical scanning is eliminated, patient exposure dose can be reduced.
  - Wide Volume Scan
    Wide volume scan is an axial scan mode used to scan ranges exceeding 160mm. Scanning is performed while the patient couch is moved before each shot. The multiple data sets are automatically combined to a wide volume, when combined with ECG gating whole thorax low-dose gated vascular studies can be acquired.
  - Helical Scan
    160-detector row ultrahelical ensures fast motion-free scans, perfectly suited for trauma applications. For higher image quality, the sampling rate has been increased to over 2900 views per second.
  - Functional Scanning
  The Aquilion ONE is developed for functional imaging, an imaging method that is not covered with conventional systems. Discover the world of dynamic blood flow, joint movement or breathing lungs and widen your scope to new fields of diagnoses.
  - Dynamic Volume Scan
    In head examinations, blood flow dynamics can be assessed and quantified with perfusion software. In orthopedic examinations, dynamic movement of joints etc. can be observed by performing scanning during patient motion. In chest examinations, lung function can be observed during free breathing. In angiographic examinations blood flow can be observed during the injection of contrast. Dynamic volume imaging is a revolutionary development in CT.
- Integrated Dose Reduction
  
  Minimization of the radiation dose is a high priority for all medical imaging practitioners. The dose has to be adjusted appropriately according to the size and shape of each patient. Automatic exposure control systems have proven to be useful in doing this while maintaining diagnostic image quality.
  
  Canon’s ^SUREExposure 3D Adaptive exposure control system is fully integrated into the imaging chain and can therefore calculate the minimum radiation exposure required for each examination of each patient. With the inclusion of Adaptive Iterative Dose Reduction 3D (AIDR 3D) in the scan protocol, the exposure dose is automatically reduced by up to 75% relative to a scan reconstructed with filtered back projection.
  
  AIDR 3D is a sophisticated algorithm that has been designed to work in both the raw data and reconstruction domains. The collective AIDR 3D process results in robust noise reduction, which is essential for achieving ultra-low-dose examinations in routine clinical imaging. This iterative algorithm is superior to non-iterative approaches in removing background noise while preserving diagnostic information.
- FIRST: The Latest In Iterative Reconstruction
  The first thing to know about FIRST (Forward projected model-based Iterative Reconstruction SoluTion) is that it is easy to use. It makes ultra-low dose iterative reconstruction, a simple and automated process that fits seamlessly into the daily workflow.
  Radiologists who want to look under the hood and study the engine driving this technological break-through will notice “FIRST means fast”. Canon accelerated computational throughput to bring their iterative reconstruction technique to the clinic where extensive reconstruction times are not acceptable. In FIRST, a reconstruction from the original (measured) projection data is performed with traditional FBP to create a seed image. This image then undergoes forward projection to create a forward projected dataset (essentially a projection summation of HU values along each ray path projection). The forward projection data is then compared against the original projection data to identify the differences between the both data. This essentially identifies errors in the FBP reconstruction, which are compensated for. A subsequent correction step is then performed to update the seed image. This is a sophisticated process because additional information concerning the focal spot size (optics model), photoelectric noise (statistical model), the cone beam trajectory (cone beam model), and the exact scan parameters (system model) are utilized in the update process.
  
  This process is iteratively repeated until the differences between the original (measured) projection data and the forward projection data are minimal, ensuring that a highly accurate image of the patient is produced with increased spatial resolution and low contrast media. Because this process is coupled with anatomically based noise regularization, FIRST is incredibly robust for data with extremely low photon counts, which translates to an opportunity to achieve significant reductions in radiation dose for all examinations.
  
  Available for the Aquilion ONE family of CT systems, FIRST improves high-contrast spatial resolution while making exams safer for patients by providing ultra-low dose examinations.
  
  Following Canon’s long-standing philosophy of minimizing dose for all patients, FIRST:
  
  Is integrated into ^SUREExposure 3D, ensuring automatic dose reduction
  
  Requires as little as 3 minutes for full volumetric reconstruction
  
  Reconstructs in parallel with InstaView realtime reconstruction
  
  Delivers unsurpassed natural-looking image quality due to anatomical modeling depending on the patient’s anatomy
  
  FIRST In Routine Clinical Practice
  
  Original Reconstruction
  
  FIRST
  
  Original Reconstruction
  
  FIRST
- Ultra Low Dose – Technology Designed To Minimize Dose
  Aquilion ONE incorporates a variety of advanced technologies into a new generation platform to ensure high quality image while minimizing the exposure dose.
  - Active Collimator
    The active collimator eliminates X-rays that are not used for image reconstruction in helical scanning. The collimator operates automatically at the start and end of scan range limiting the extent of the X-ray beam, permitting further dose reduction. With active collimation exposure can be reduced by up to 20%.
  - ^SURECARDIO Prospective – Overcome The Unexpected
    Aquilion ONE performs coronary angiography using a single rotation axial scan. This not only ensures uniformity in the Z-axis, but the short scan time also reduces the need for contrast. With ^SURECARDIO Prospective even patients with arrhythmia can be successfully scanned while the patient dose is maintained as low as possible. An optimum scan at the lowest dose for every patient, every time.
  - ^SUREEXPOSURE 3D Adaptive
    ^SUREExposure 3D Adaptive is a function that continuously modulates the exposure dose in the X, Y, and Z directions according to the patient’s body shape and size. Using dose modulation alone, exposure already can be reduced by up to 40%.
  - Variable Helical Pitch
    Variable Helical Pitch (vHP) allows prescribing an exam that automatically changes the helical pitch at a user-defined location during acquisition without stopping the table motion. For example, in a CTA aorta examination, ECG-gated scanning with a slow pitch is performed for the thoracic, seamlessly switching to non-gated scanning with a faster pitch for the abdominal aorta. vHP provides an optimized workflow and short scan times when performing combined studies while significantly reducing contrast and radiation dose.
  - ConeXact With Double Slice Technology
  Taking full advantage of the coneXact technology, acquired volume data can be reconstructed in double density, resulting in a more true-to-original reconstruction in MPR and 3D rendered images.
  - Hybrid View
    Save time and storage space with Caon’s hybrid reconstruction kernels. These newly introduced iterative reconstruction algorithms provide sharp lungs and excellent soft tissue resolution in one image. Reading times are shortened as you only need to concentrate on a single series to make a definitive diagnosis.
- ONE Design
  Canon’s vision for the welfare of your patients extends beyond the scan room.
  
  Patient comfort and ease of use have been in the forefront during the design of the Aquilion ONE. Environmentally friendly manufacturing processes and unique hybrid drive technology contribute to the wellbeing of future generations.
  ONE Gantry
  
  Canon’s Medical Division has drawn on the experience and expertise of Toshiba Corporation’s many advanced technologies to develop the revolutionary Aquilion ONE gantry. Routinely rotating at 0.350 seconds per rotation the Aquilion ONE delivers a high level of precision and image quality. The gantry is designed to even handle faster rotation speeds and can be upgraded to Aquilion ONE ViSION level.
  
  A wide 78cm open bore ensures even the largest of patients remain at ease during scanning. This design also offers superior patient access to physicians during interventional procedures.
  
  ONE Table
  
  The Aquilion ONE tabletop has been engineered for comfort for your patients, and ease of positioning for your technologists. The industry’s widest table top ensures a feeling of extra security for your patients during positioning and scanning.
  
  Tech Assist Lateral Slide is another Canon first providing the technologist unparalleled ease in positioning patients without physical strain.
  
  ONE Hybrid
  
  The hybrid drive converts energy during deceleration of the gantry and generates electricity that is recycled to power gantry components. A thoughtful design feature that minimizes power consumption and reduces carbon footprint.
  
  The Aquilion ONE represents Canon Corporation’s commitment to the environment and is certified as “Environmentally Conscious Product”.
- ONE Workflow
  Do more in less time using advanced reconstruction and visualization technology designed to streamline workflow and shorten time to diagnosis. Integration of a suite of advanced technologies ensures that high throughput can be maintained while delivering consistent, high-quality examinations.
  Reconstruction Speed
  
  Powerful reconstruction architecture delivers at a maximum rate of 50 images per second, permitting the routine use of AIDR 3D iterative reconstruction technology in any fast paced environment.
  
  Multi View
  
  Multi View allows all reconstruction parameters to be pre-programmed into every examination protocol. Axial, coronal and sagittal reconstructions are performed automatically without a single mouse click. Even rendering options such as thick slab MIP images can be automatically generated expediting time to diagnosis. Simply plan the scan and go!
  
  InstaView
  
  In 2004, Canon (former Toshiba) was the first manufacturer to deliver realtime image reconstruction. Second generation InstaView technology provides near-instant display and review now with full resolution images. High-quality realtime image review is perfectly suited for the emergency patient, where every second to diagnosis counts.
  
  Hybrid View
  
  Save time and storage space with Canon’s hybrid reconstruction kernels. These newly introduced iterative reconstruction algorithms provide sharp lungs and excellent soft tissue resolution in one image. Reading times are shortened as you only need to concentrate on a single series to make a definitive diagnosis.
- Perfusion
  Transform your diagnostic capabilities from morphological to physiological diagnosis. Scans are performed effortlessly with low-dose parameters.
  - Diagnose lesions that cannot be seen with traditional static imaging
  - Add certainty to the classification of tumors with blood flow quantification
  - Monitor tumor progression and follow-up response to treatment
  - Reduce the need for additional imaging tests or biopsy
  - Body Perfusion
  Body perfusion software analyzes the blood perfusion of an organ from dynamic scan images. The perfusion application can provide additional information for the diagnosis, treatment and follow-up of lesions.
  - Whole-organ temporal uniformity
  - Fully automated non-rigid volume position-matching software
  - Low-dose perfusion scan protocol
  - Interactive control of functional color overlay on morphological images
  - Brain Perfusion
  The Neuro ONE protocol allows acquisition of multiple low-dose volume scans of the entire brain during contrast infusion to provide whole-brain perfusion and whole-brain dynamic vascular analysis in one examination.
  - Myocardial Perfusion
  The results of the CorE320 multicenter trial have shown that coronary CTA has the potential to become a diagnostic tool equivalent to conventional coronary angiography. Following this trial, Myocardial Perfusion has been developed as an advanced application for quantitative perfusion analysis.
  - Whole-heart acquisition in a single temporally uniform volume
  - Accurate diagnosis: Myocardial Perfusion combined with coronary CTA can accurately assess myocardial perfusion and identify the coronary arteries responsible for ischemia
  - Ultra-low dose: All required perfusion data can be obtained by just one scan
- ONE Family – Advanced Clinical Applications
  - Lung Volume Analysis
  Lung Volume Analysis automatically identifies tissues in the lung fields with a CT number lower than the specified value (regions of pulmonary emphysema) for visualization and analysis.
  - Dual Energy
  Dual Energy helical scanning alternates between high and low kV with each gantry rotation. Also the mA is automatically adjusted for the two different energies to ensure a matched signal-to-noise ratio which increases the accuracy of dual energy analysis. In addition, Aquilion ONE can automatically turn X-ray exposure off when the X-ray tube passes the front of the patient; thus, minimizing exposure to radiosensitive organs such as the breasts and eye lenses.
  ^SURECARDIO Prospective – Overcome The Unexpected
  
  Aquilion ONE performs coronary angiography using a prospectively triggered helical technique. This ensures uniformity in the Z-axis compared to step-and-shoot techniques.
  
  ^SURECardio Prospective includes Canon’s proprietary arrhythmia rejection software which recognizes irregular heart rhythm and controls scan exposure accordingly to ensure a diagnostic study every time, and so minimize repeat examinations.
- Maximizing Clinical Capability
  Aquilion ONE supports Canon’s sophisticated suite of ^SURETechnologies and other advanced software tools to improve image quality, lower dose requirements and deliver the scan for diagnosis fastest in the industry. Continuous development of optional field upgradable software enhancements means that when it comes to maintaining state-of-the-art capabilities, your investment is always protected.
  
  For Cardiac:
  - ^SURECardio Prospective
  - ^SUREPlaque
  - ^SURECardio Scoring
  - Cardiac Function Analysis
  For Body:
  - Vessel View
  - Colon View
  - Fat Index View
  For Neuro:
  - ^SURESubtraction
  - CBP Study
  Others:
  - 3D CT Fluoroscopy
  - Dental Analysis

FIRST In Routine Clinical Practice